Publications
Publications
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- Hu P, Rychik J, Zhao J, Bai H, Bauer A, Yu W, Rand EB, Dodds KM, Goldberg DJ, Tan K, Wilkins BJ, Pei L. Single-cell multiomics guided mechanistic understanding of Fontan-associated liver disease. Sci Transl Med. 2024 Apr 24;16(744):eadk6213. doi: 10.1126/scitranslmed.adk6213. Epub 2024 Apr 24. PMID: 38657025. (Click here to read the page)
- Gan L, Pei L. Epigenetic Regulation of Heart-ECHS∗ . J Am Coll Cardiol Basic Trans Science. 2022 Apr, 7 (4) 363–365.
- Zhao J, Pei L. Cardiac Endocrinology: Heart-Derived Hormones in Physiology and Disease. J Am Coll Cardiol Basic Trans Science. 2020 Sep, 5 (9) 949–960.
- Hu P, Liu J, Zhao J, Wilkins BJ, Lupino K, Wu H, Pei L. Erratum: Single-nucleus transcriptomic survey of cell diversity and functional maturation in postnatal mammalian hearts. Genes Dev. 2019 Nov 1;33(21-22):16131.
- Zhao J, Lupino K, Pei L. Single Cell Analysis of Postnatal Heart Development and Disease. Circulation Research. 2019 Oct, 16 (125) A281.
- Hu P, Liu J, Zhao J, Wilkins BJ, Lupino K, Wu H, Pei L: Single-nucleus transcriptomic survey of cell diversity and functional remodeling in the postnatal developing hearts. Genes & Development 32(19-20): 1344-57, Oct 2018.
- Zhao J, Lupino K, Wilkins BJ, Qiu C, Liu J, Omura Y, Allred AL, McDonald C, Susztak K, Barish GD, Pei L: Genomic integration of ERRγ-HNF1β regulates renal bioenergetics and prevents chronic kidney disease. Proc Natl Acad Sci USA 115(21): E4910-E4919, May 2018.
- Li J, Liu J, Lupino K, Liu X, Zhang L, Pei L: GDF15 maturation requires proteolytic cleavage by PCSK3, 5 and 6. Molecular and Cellular Biology 38(21): e00249-18, Oct 2018 Notes: DOI 10.1128/MCB.00249-18.
- Pei L, Wallace DC : Mitochondrial Etiology of Neuropsychiatric Disorders. Biological Psychiatry 83(9): 722-730, May 2018.
- Wang T, Liu J, McDonald C, Lupino K, Zhai X, Wilkins BJ, Hakonarson H, Pei L : GDF15 is a heart-derived hormone that regulates body growth. EMBO Molecular Medicine 9: 1150-1164, 2017.
- Wang T, McDonald C, Petrenko NB, Leblanc M, Giguere V, Evans RM, Patel VV, and Pei L: ERRalpha and ERRgamma are essential coordinators of cardiac metabolism and function. Mol Cell Biol. 35(7): 1281-1298, 2015.
- Pei L, Mu Y, Leblanc M, Alaynick W, Barish GD, Pankratz M, Tseng TW, Kaufman S, Liddle C, Yu RT, Downes M, Pfaff SL, Auwerx J, Gage FH, Evans RM: Dependence of hippocampal function on ERRγ regulated mitochondrial metabolism. Cell Metab 21(4): 628-636, 2015.
- Pei L, Leblanc M, Barish G, Atkins A, Nofsinger R, Whyte J, Gold D, He M, Kawamura K, Li H-R, Downes M, Yu R, Powell HC, Lingrel JB, Evans RM: Thyroid hormone receptor repression is linked to type I pneumocyte associated respiratory distress syndrome. Nat Med 17(11): 1466-1472, 2011.
- Pei L, and Evans RM: Retrofitting fat metabolism. Cell Metab 9(6): 483-484, 2009.
- Pei L, Waki H, Vaitheesvaran B, Wilpitz DC, Kurland IJ, and Tontonoz P: NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism. Nat Med 12(9): 1048-1055, 2006.
- Pei L, Castrillo A, Chen M, Hoffmann A, Tontonoz P: Induction of NR4A Orphan Nuclear Receptor Expression in Macrophages in Response to Inflammatory Stimuli. J Biol Chem 280(32): 29256-29262, 2005.
- Pei L, Castrillo A, and Tontonoz P: Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77. Mol Endocrinol 20(4): 786-794, 2006.
